Lisa Learns Aloud

The American Revolution day by day. May and June 1775. Red Lines and Scottish Rebels.

One of the things becoming apparent is that although the colonies were separately working to form militias and safety committees, it was the Carolinas—North and South—that were among the first to adopt declarations moving toward independence. In May 1775, North Carolina adopted the Mecklenburg Resolves. These resolutions challenged royal authority in the colonies, declaring that anyone who accepted a royal commission would be considered an enemy of the people. It was a clear red line.
The Governor of North Carolina, along with some other high-ranking British authorities, relocated to British ships anchored offshore for their own safety. The Provincial Congress of South Carolina also asserted solidarity with the other colonies. So the Carolinas were leading the early push in that direction.

A theory of mine (from too many viewings of Braveheart and Outlander) is:
At the time, a significant number of Scots were living in North and South Carolina. The Scots’ history and experiences under British rule had been tumultuous. They already knew what it was like to live under the thumb of the British. Those experiences probably made them suspicious of British rule—they didn’t want to live under it again and were unwilling to put up with the restrictions the British were imposing.